Bodyguards are the fighters that protect the demon bosses. All demons have five bodyguards. Before one can actually battle the demon, they have to beat their five bodyguards. Bodyguards have their own speaking roles (except Shin).
The first three of Wasp's "bodyguards" are the members of New Blood, a group consisting of crew members that have rebelled against her. The last two bodyguards are a few men that are still loyal to her.
Widow's "bodyguards" are mainly composed of men that have been charmed. The only exception is Puma, a woman who serves Widow to help her achieve her ambitions. Most bodyguards attack Shadow in an attempt to eliminate the competition, because they are mistaken in the belief that Shadow desires Widow as they do; He merely wants to obtain her Demon Seal, and has no interest in her whatsoever. After being defeated by Shadow they are released from Widow's spell.
Titan's bodyguards are warriors whose survived the powerful emission of shadow energy from the Gates of Shadows, but lacked the will to hold too much energy. They claims that they are superior than the demons and have defeated them.